Overview:
The general form of Fischer esterification mechanism is as follows:
The first step involves protonation of the carbonyl oxygen, followed by the nucleophillic attack of the alcohol.
Then a loss and regain of a proton,
followed by loss of water as electrons from the alcohol oxygen kick down to form the double bond. Loss of a proton yields the ester.
Example of fischer esterification:


Wednesday, March 21, 2007
Fischer esterification mechanism
Posted by Organic Chemistry at 1:08 PM
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